PHYSICAL ACTIVITY CORRELATES WITH CARDIOVASCULAR FUNCTION IN PATIENTS WITH DUCHENNE MUSCULAR DYSTROPHY
نویسندگان
چکیده
منابع مشابه
Detection of the Duplication in Exons 56-63 of Duchenne Muscular Dystrophy Patients with MLPA
Background Duchenne Muscular Dystrophy (DMD) is a deadly X-linked recessive disorder. This genetic disorder affects 1 among 3,500-5,000 males in the world. The majority of the patients are male, due to the type of inheritance. It affects most of the skeletal, the respiratory, and cardiac muscles, causing these vital organs to contract and eventually mortality.<br...
متن کاملScoliosis in patients with Duchenne muscular dystrophy.
espite recent research developments, Duchenne muscular dystrophy remains a fatal neuromuscular disease, affecting two to three boys in 10,000. It is an inherited X-linked recessive condition caused by a frameshift mutation in the dystrophin gene at the Xp21.2 locus of the X chromosome. Dystrophin is a large cell-membrane protein involved in calcium transport in the muscle cell. Boys with Duchen...
متن کاملExperimental Models of Duchenne Muscular Dystrophy: Relationship with Cardiovascular Disease
Almost every boy that has Duchenne Muscular Dystrophy (DMD) will develop cardiac problems. Whereas, it used to be respiratory problems that was the main cause of death in these DMD boys; with the advent of better respiratory care it is now the cardiac involvement that is becoming the most common cause of their death. Once the heart is affected, there is progressive deterioration in the function...
متن کاملP164: Adeno-Associated Viral Vectors in Duchenne Muscular Dystrophy
Duchenne muscular dystrophy (BMD) is an inherited X-link disease. The incidence of this muscle-wasting disease is 1:5000 male live births. Mutation in the gene coding for dystrophin is the main cause of BMD. Most cases of this disease succumb to respiratory and cardiac failure in 3rd to 4th decades. The slow progression of BMD and recent achievement of gene therapies make it as an appropriate c...
متن کاملUpper limb function in adults with Duchenne muscular dystrophy.
OBJECTIVE To determine upper limb function and associated factors in adults with Duchenne muscular dystrophy. DESIGN Cross-sectional study. SUBJECTS A sample of 70 men with Duchenne muscular dystrophy (age range 20-43 years). METHODS General motor function and, in particular, upper limb distal motor function, were assessed with the Motor Function Measure. Muscle strength and range of moti...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2021
ISSN: 0735-1097
DOI: 10.1016/s0735-1097(21)01830-1